Course # DL-989: Neutrophilia
by Helen M. Sowers, MA, CLS - Dept. of Biological Science (retired) - California State University, East Bay - Hayward, CA
by Dora W. Goto, MS, CLS, MLS(ASCP)CM - Laboratory Consultant - University HealthCare Alliance - Hayward, CA
Approved for 1.0 CE
Level of Difficulty: Basic
The production and distribution of normally functioning neutrophils is vital to host defenses. In order to understand the normal condition compared to changes that occur in disease states, the development, structure, function, and kinetics of neutrophils will be discussed.
There are a number of causes for increase in neutrophils. In this course we present two cases of neutrophilia and compare the etiology, laboratory findings, and microscopic morphology for each. Other causes of neutrophilia will be discussed.
After completing this course the participant will be able to:
1. Outline the maturation stages of neutrophils.
2. Discuss how neutrophils protect the body against foreign invaders.
3. Explain the difference between shift neutrophilia and absolute neutrophilia.
4. Compare the microscopic morphology of neutrophils in infections to those in chronic myelocytic leukemia.
5. List other causes of neutrophilia.