Course # DL-966: Cystic Fibrosis and Microbial Infections

by Lucy Treagan, Ph.D. - Professor of Biology Emerita - University of San Francisco - San Francisco, CA

Approved for 2.0 CE
Level of Difficulty:Intermediate


Cystic fibrosis is a genetic disorder resulting from mutations in a gene on the long arm of chromosome 7. This disorder is found predominantly in Caucasian populations of European ancestry. The gene defect results in numerous medical problems for the patient. These problems include progressive lung disease and multiple organ dysfunction caused by abnormal electrolyte transport. Many organs are affected, including the lungs, pancreas, intestines, sweat glands, and kidneys.


Upon completion of this course the participant will be able to:

1. discuss the genetic basis of cystic fibrosis.

2. describe clinical symptoms.

3. list diagnostic methods.

4. explain the significance of microbial infections in cystic fibrosis patients.

5. list microorganisms involved in these infections.

6. outline a practical approach to identification of microbial pathogens isolated from cystic fibrosis patients.

7. summarize therapies useful in cystic fibrosis.

8. describe current experimental studies.


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